APDB: a web server to evaluate the accuracy of sequence alignments using structural information
|Title||APDB: a web server to evaluate the accuracy of sequence alignments using structural information|
|Publication Type||Journal Article|
|Year of Publication||2006|
|Authors||Armougom F, Poirot O, Moretti S, Higgins DG, Bucher P, Keduas V, Notredame C|
|Date Published||Oct 1|
|Keywords||Algorithms, Amino Acid Sequence, Conserved Sequence, Internet, Molecular Sequence Data, Proteins/ chemistry, Sequence Alignment/ methods, Sequence Analysis, Protein/ methods, Sequence Homology, Amino Acid, Software, User-Computer Interface|
The APDB webserver uses structural information to evaluate the alignment of sequences with known structures. It returns a score correlated to the overall alignment accuracy as well as a local evaluation. Any sequence alignment can be analyzed with APDB provided it includes at least two proteins with known structures. Sequences without a known structure are simply ignored and do not contribute to the scoring procedure. AVAILABILITY: APDB is part of the T-Coffee suite of tools for alignment analysis, it is available on www.tcoffee.org. A stand-alone version of the package is also available as a freeware open source from the same address.