Identifying protein-coding genes in genomic sequences.

TitleIdentifying protein-coding genes in genomic sequences.
Publication TypeJournal Article
Year of Publication2009
AuthorsHarrow J, Nagy A, Reymond A, Alioto T, Patthy L, Antonarakis SE, Guig├│ R
JournalGenome Biol.
Volume10
Pagination201
Abstract

The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets.

URLhttp://dx.doi.org/10.1186/gb-2009-10-1-20
DOI10.1186/gb-2009-10-1-201