Large-scale assignment of orthology: back to phylogenetics?
|Title||Large-scale assignment of orthology: back to phylogenetics?|
|Publication Type||Journal Article|
|Year of Publication||2008|
ABSTRACT: Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies.