Large-scale assignment of orthology: back to phylogenetics?

TitleLarge-scale assignment of orthology: back to phylogenetics?
Publication TypeJournal Article
Year of Publication2008
AuthorsGabaldón T
JournalGenome Biol.
Volume9
Pagination235
Date PublishedOct
Abstract

ABSTRACT: Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies.

URLhttp://dx.doi.org/10.1186/gb-2008-9-10-23
DOI10.1186/gb-2008-9-10-235