Promoter-like epigenetic signatures in exons displaying cell type-specific splicing

TitlePromoter-like epigenetic signatures in exons displaying cell type-specific splicing
Publication TypeJournal Article
Year of Publication2015
AuthorsCurado J, Iannone C, Tilgner H, Valcárcel J, Guigó R
JournalGenome biology
Volume16
Pagination236
Date PublishedOct
ISSN1474-760X
Abstract

Pre-mRNA splicing occurs mainly co-transcriptionally, and both nucleosome density and histone modifications have been proposed to play a role in splice site recognition and regulation. However, the extent and mechanisms behind this interplay remain poorly understood.

URLhttp://www.ncbi.nlm.nih.gov/pubmed/26498677
DOI10.1186/s13059-015-0797-8