STRIKE: evaluation of protein MSAs using a single 3D structure.
|Title||STRIKE: evaluation of protein MSAs using a single 3D structure.|
|Publication Type||Journal Article|
|Year of Publication||2011|
|Authors||Kemena C, Taly JF, Kleinjung J, Notredame C|
Evaluating alternative multiple protein sequence alignments is an important unsolved problem in Biology. The most accurate way of doing this is to use structural information. Unfortunately, most methods require at least two structures to be embedded in the alignment, a condition rarely met when dealing with standard datasets.